| 别名 | 1,2-二溴-4-氟代苯; |
1,2-二溴-4-氟苯
1,2-Dibromo-4-fluorobenzene （订货以英文为准）
编号：D155246
CAS号：2369-37-1
分子式：C6H3BR2F
分子量：253.90
| 产品名称 | 1,2-Dibromo-4-fluorobenzene |
| 中文名称 | 1,2-二溴-4-氟苯 |
| CAS号 | 2369-37-1 |
| 分子式（M.F.） | C6H3BR2F |
| 分子量（M.W.） | 253.90 |
| Reaxys-RN | 3546082 |
技术规格
| Background: | MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 . Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53 . Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53 . |
| Applications: | WB |
| Name of antibody: | MDM2 |
| Immunogen: | Synthetic peptide of human MDM2 |
| Full name: | MDM2 oncogene, E3 ubiquitin protein ligase |
| Synonyms： | HDMX; hdm2; ACTFS |
| SwissProt: | Q00987 |
| WB Predicted band size: | 90 kDa |
| WB Positive control: | 293 and Hela cells |
| WB Recommended dilution: | 500-1000 |
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