熔点 | 323.9-325 °C |
溶解性 | Soluble in water (24 mg/ml), DMSO (88 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
存贮条件 | 储存温度 2-8°C |
应用 | An antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV. |
产品介绍 | Moxifloxacin HCl是一种第四代喹诺酮类抗菌剂。 |
备注 | Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent. |
生化机理 | Moxifloxacin Hydrochloride is the hydrochloride salt preparation of Moxifloxacin, an 8-methoxy-fluoroquinone compound with broad-spectrum bactericidal activity against gram-positive and gram-negative strains. 8-methoxy-fluoroquinones are described to inhibit the activities of Topo II (DNA gyrase) and topoisomerase IV. The 8-methoxy group of Moxifloxacin is suggested to confer a lowered propensity for resistance development as compared to other C-8 substituted quinolones, and Moxifloxacin demonstrates potent activity against wild-type and first-step gyrase- and topoisomerase IV-resistant mutants. Moxifloxacin shows activity against methicillin-susceptible staphylococci, penicillin-susceptible and penicillin-resistant pneumococci, penicillin-susceptible and penicillin-resistant viridans group streptococci, group A streptococci, M. catarrhalis, and H. influenzae in vitro. |
别名 | 盐酸莫西沙星; 1-环丙基-7-(S,S-2,8-重氮-二环[4.3.0]壬烷-8-基)-6-氟-8-甲氧-1,4-二氢-4-氧-3-喹啉羧酸盐酸盐;1-环丙基-6-氟-1,4-二氢-8-甲氧基-7-[(4aS,7aS)-十氢-1H-吡咯并[3,4-b]吡啶-6-基]-4-氧代-3-喹啉甲酸盐酸盐;Actura; Avalox; Avelox;1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride |
盐酸莫西沙星
Moxifloxacin HCl (订货以英文为准)
编号:M129861
CAS号:186826-86-8
分子式:C21H25CLFN3O4
分子量:437.89
产品名称 | Moxifloxacin HCl |
中文名称 | 盐酸莫西沙星 |
CAS号 | 186826-86-8 |
分子式(M.F.) | C21H25CLFN3O4 |
分子量(M.W.) | 437.89 |
储存条件 | 2-8°C储存 |
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