熔点 | 171-175°C |
敏感性 | 对空气敏感 |
溶解性 | Soluble in water (100 mM), ethanol (~25 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (pH 7.2) (~15 mg/ml). |
存贮条件 | 充氩保存 |
应用 | An activator of GPR35. |
生化机理 | Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35. |
别名 | (R)-O-(3,4-二羟基肉桂酰)-3-(3,4-二羟苯基)乳酸;3,4-二羟基肉桂酸;(R)-1-羧基-2-(3,4-二羟苯)乙酯(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid;3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester |
迷迭香酸
Rosmarinic acid (订货以英文为准)
编号:R109805
CAS号:20283-92-5
分子式:C18H16O8
分子量:360.31
产品名称 | Rosmarinic acid |
中文名称 | 迷迭香酸 |
CAS号 | 20283-92-5 |
分子式(M.F.) | C18H16O8 |
分子量(M.W.) | 360.31 |
储存条件 | 充氩 |
Reaxys-RN | 1773831 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H315,H319,H335,H413 |
警示性声明 | P261,P305+P351+P338 |
个人防护设备 | dust mask type N95 (US),Eyeshields,Gloves |
RTECS | RZ1925000 |
WGK德国 | 3 |
风险声明 (欧洲) | 36/37/38 |
安全声明(欧洲) | 26,36 |
危害码(欧洲) | Xi |
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