溶解性 | DMSO 52 mg/mL Water <1 mg/mL Ethanol 52 mg/mL |
存贮条件 | 储存温度2-8℃ |
应用 | A potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis |
产品介绍 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
备注 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
生化机理 | Ferrostatin-1 (2 μM) prevents erastin-induced ferroptosis in cancer cells, as well as glutamate-induced cell death in postnatal rat brain slices. Ferrostatin-1 is a lipid ROS scavenger, with the N-cyclohexyl moiety serving as a lipo-philic anchor within biological membranes. Ferrostatin-1 Ferrostatin-1 is a potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis. Ferrostatin-1 prevents ferroptopic cell death in cancer cells and glutamate-induced toxicity in organotypic rat brain slices. It appears that Ferrostatin-1 controls lipid soluble ROS. |
别名 | ;3-Amino-4-cyclohexylaminobenzoic Acid Ethyl Ester; |
Ferrostatin-1 (Fer-1),雌激素诱导的肥大病抑制剂
Ferrostatin-1 (Fer-1) (订货以英文为准)
编号:F129882
CAS号:347174-05-4
分子式:C15H22N2O2
分子量:262.35
产品名称 | Ferrostatin-1 (Fer-1) |
中文名称 | Ferrostatin-1 (Fer-1),雌激素诱导的肥大病抑制剂 |
CAS号 | 347174-05-4 |
分子式(M.F.) | C15H22N2O2 |
分子量(M.W.) | 262.35 |
储存条件 | 2-8°C储存;避光;充氩 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H302 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | KF4997000 |
WGK德国 | 3 |
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