| 敏感性 | 对热和光敏感 |
| 溶解性 | Soluble in water (125 mg/ml), ethanol (70 mg/ml at 25 °C), chloroform (1:3), DMSO (70 mg/ml at 25 °C), and dilute aqueous acid. |
| 应用 | A selective ST, SLC6A2, and DAT inhibitor |
| 产品介绍 | Clomipramine HCl 是Clomipramine的盐酸盐，抑制5-羟色胺转运蛋白（SERT），去甲肾上腺素转运体（NET）和多巴胺转运蛋白（DAT），Ki分别为0.14， 54和3 nM。 |
| 备注 | Clomipramine hydrochloride (Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. |
| 生化机理 | Clomipramine hydrochloride (Anafranil) is a hydrochloride salt of clomipramine which is an ST (serotonin transporter/SERT), SLC6A2 (norepinephrine transporter/NET), and DAT (dopamine transporter) blocker with Ki of 0.14, 54 and 3 nM, respectively. Clomipramine hydrochloride is a tricyclic antidepressant, a norepinephrine-reuptake inhibitor, and an antiobsessional drug. Clomipramine hydrochloride is an inhibitor of D2 receptor (Ki = 162 nM), D3 receptor (Ki = 30 nM), AR (α1-adrenergic receptor, Ki = 3.2 nM), α2-adrenergic receptor (Ki = 525 nM), H1 receptor (Ki = 31 nM), mACh receptors (Ki = 37 nM), 5-HT2A receptor (Ki = 36 nM), 5-HT2C receptor (Ki = 65 nM), 5-HT3 receptor (Ki = 85 nM), 5-HT6 receptor (Ki = 54 nM), 5-HT7 receptor (Ki = 127 nM), D1 receptor (Ki = 219 nM). |
| 别名 | 盐酸氯米帕明;氯丙咪嗪盐酸盐;Anafranil hydrochloride;Clomipramine hydrochloride |
氯丙咪嗪盐酸盐
Clomipramine HCl （订货以英文为准）
编号：C129687
CAS号：17321-77-6
分子式：C19H24CL2N2
分子量：351.31
| 产品名称 | Clomipramine HCl |
| 中文名称 | 氯丙咪嗪盐酸盐 |
| CAS号 | 17321-77-6 |
| 分子式（M.F.） | C19H24CL2N2 |
| 分子量（M.W.） | 351.31 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Warning |
| 危害声明 | H302-H413 |
| WGK德国 | 1 |
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