| 溶解性 | 25°C: DMSO 32 mg/mL (93.62 mM);Water <1 mg/mL (<1 mM);Ethanol <1 mg/mL (<1 mM) |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | An inhibitor of IGF-1R autophosphorylation. |
| 产品介绍 | PQ 401抑制IGF-1R区域自磷酸化，IC50为低于1 μM。 |
| 备注 | PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM. |
| 生化机理 | PQ401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation. The mechanism of inhibition likely involves indirect blocking of ATP binding. PQ401 also decreases IGF-1R-dependent tumor cell growth in vitro. |
| 别名 | N-(5-氯-2-甲氧基苯基)-N'-(2-甲基-4-喹啉基)脲;PQ 401;PQ-401;IGF-1R Inhibitor II;N-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)-urea |
PQ 401,细胞渗透性IGF1R抑制剂
PQ 401 （订货以英文为准）
编号：P125823
CAS号：196868-63-0
分子式：C18H16CLN3O2
分子量：341.79
| 产品名称 | PQ 401 |
| 中文名称 | PQ 401,细胞渗透性IGF1R抑制剂 |
| CAS号 | 196868-63-0 |
| MDL编码 | MFCD00160558 |
| 分子式（M.F.） | C18H16CLN3O2 |
| 分子量（M.W.） | 341.79 |
| 储存条件 | 2-8°C储存 |
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