存贮条件 | 储存温度-20°C |
应用 | 本品能使胃酸作用后凝固的蛋白质分解成胨,但不能进一步使之分解成氨基酸。其消化力以含0.2%~0.4%盐酸(PH=1.6~1.8)是为最强。胃蛋白酶是一种用于消化蛋白质的肽酶,常用于从抗体制备Fab片段。来自猪胃粘膜的胃蛋白酶已被用于水解小鼠的干燥宫颈样本。胃蛋白酶切割可用于产生抗体的F(ab′)2 片段。 |
产品介绍 | Pepsin is an acidic protease. Its inactive zymogen precursor, pepsinogen, is produced in the stomach mucosa. There are several pepsins designated A, B, C, and D. Pepsin A, the major component, has a molecular weight of 35,000 daltons and an optimum pH of approximately 1.0 for substrates such as casein or hemoglobin if the substrate is native protein. Pepsin cleaves proteins preferentially at carboxylic groups of aromatic amino acids such as phenylalanine and tyrosine. It will not cleave at bonds containing valine, alanine or glycine. Pepsin is assayed based on the method of Anson J. Gen. Physiol., 22, 79 (1938) using hemoglobin as the substrate. Pepsin is unstable above pH 6. |
备注 | Two times crystallized from dilute alcohol. A lyophilized powder. |
生化机理 | 优先裂解:P1 和 P1′ 位的疏水性和芳族残基。降解胰岛素 β 链中的 Phe-Val、Gln-His、Glu-Ala、Ala-Leu、Leu-Tyr、Tyr-Leu、Gly-Phe、Phe-Phe 和 Phe-Tyr 键 |
别名 | 胃液素;胃朊酶;蛋白酵素;酸腈酶;胃酶;胃蛋白酶 A;Pepsin from porcine gastric mucosa; Pepsin A; Pepsin from hog stomach; Pepsini pulvis; Pepsin powder |
胃蛋白酶 来源于猪胃
Pepsin from Porcine Stomach (订货以英文为准)
编号:P128678
CAS号:9001-75-6
分子式:N.A.
产品名称 | Pepsin from Porcine Stomach |
中文名称 | 胃蛋白酶 来源于猪胃 |
CAS号 | 9001-75-6 |
分子式(M.F.) | N.A. |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
信号词 | Danger |
危害声明 | H315,H319,H334,H335 |
警示性声明 | P261,P305+P351+P338,P342+P311 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
RTECS | RU4950000 |
WGK德国 | 1 |
风险声明 (欧洲) | R36/37/38;R42 |
安全声明(欧洲) | S22;S24;S26;S36/37 |
危害码(欧洲) | Xn |
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