伊贝沙坦

Irbesartan (订货以英文为准)

编号:I129263
CAS号:138402-11-6
分子式:C25H28N6O
分子量:428.53
货号 品牌 包装 目录价 您的价格 库存 数量 购买
I129263-5g 阿拉丁 5g ¥59.90
I129263-1g 阿拉丁 1g ¥29.90
I129263-25g 阿拉丁 25g ¥199.90
I129263-100g 阿拉丁 100g ¥759.90
产品名称 Irbesartan
中文名称 伊贝沙坦
CAS号 138402-11-6
MDL编码 MFCD00864464
分子式(M.F.) C25H28N6O
分子量(M.W.) 428.53
储存条件 2-8°C储存
溶解性Soluble in DMSO (>25 mg/ml), ethanol (~0.5 mg/ml), methanol, DMF (~20 mg/ml), and water (<1 mg/ml at 25 °C).
存贮条件储存温度2-8℃
应用An angiotensin II type 1 (AII1)-receptor antagonist.
产品介绍Irbesartan是一种高效的特定血管紧张素II 1型(AT1)受体拮抗剂,IC50为1.3 nM。
备注Irbesartan (SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.
生化机理Irbesartan is a highly potent and selective antagonist of the AT1 (angiotensin II type 1) receptor with an IC50 = 1.3 nM. This compound has no affinity for AT2 receptors. Pretreatment with irbesartan decreases angiotensin II-induced apoptosis in rat vascular smooth muscle cells by blocking angiotensin II internalization in a concentration-dependent manner.
别名伊贝沙坦; 2-丁基-3-[4-[2-(1H-四唑-5-基)苯基]苄基]-1,3-二氮杂螺-[4.4]壬-1-烯-4-酮;BMS-186295;SR-47436;Avapro;3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one;2-Butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
Merck Index2538
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H317
警示性声明P280
个人防护设备dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECSGM7650000
WGK德国3
风险声明 (欧洲)43
安全声明(欧洲)36
危害码(欧洲)Xi
搜索质检报告(COA)
搜索MSDS
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