| 溶解性 | Soluble in DMSO (>25 mg/ml), ethanol (~0.5 mg/ml), methanol, DMF (~20 mg/ml), and water (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | An angiotensin II type 1 (AII1)-receptor antagonist. |
| 产品介绍 | Irbesartan是一种高效的特定血管紧张素II 1型(AT1)受体拮抗剂，IC50为1.3 nM。 |
| 备注 | Irbesartan (SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. |
| 生化机理 | Irbesartan is a highly potent and selective antagonist of the AT1 (angiotensin II type 1) receptor with an IC50 = 1.3 nM. This compound has no affinity for AT2 receptors. Pretreatment with irbesartan decreases angiotensin II-induced apoptosis in rat vascular smooth muscle cells by blocking angiotensin II internalization in a concentration-dependent manner. |
| 别名 | 伊贝沙坦; 2-丁基-3-[4-[2-(1H-四唑-5-基)苯基]苄基]-1,3-二氮杂螺-[4.4]壬-1-烯-4-酮;BMS-186295;SR-47436;Avapro;3-Butyl-2-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one;2-Butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one |
伊贝沙坦
Irbesartan （订货以英文为准）
编号：I129263
CAS号：138402-11-6
分子式：C25H28N6O
分子量：428.53
| 产品名称 | Irbesartan |
| 中文名称 | 伊贝沙坦 |
| CAS号 | 138402-11-6 |
| 分子式（M.F.） | C25H28N6O |
| 分子量（M.W.） | 428.53 |
| 储存条件 | 2-8°C储存 |
| Merck Index | 2538 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Warning |
| 危害声明 | H317 |
| 警示性声明 | P280 |
| 个人防护设备 | dust mask type N95 (US),Eyeshields,Faceshields,Gloves |
| RTECS | GM7650000 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | 43 |
| 安全声明（欧洲） | 36 |
| 危害码（欧洲） | Xi |
搜索质检报告(COA)
搜索MSDS
相关产品
¥ 3.40
jx2135471-1m
¥ 75.00
130117003-1箱
¥ 85.00
130117004-1箱
¥ 91.00
F444400-1支
¥ 109.90
R749970-50ml
¥ 90.00
jx1325647-1支
党沛 
