溶解性 | DMSO 97 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
备注 | MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM. |
生化机理 | MLN0905, a small-molecule PLK1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma. PLK1 inhibition leads to pharmacodynamic pHisH3 modulation and significant antitumor activity in multiple DLBCL models. MLN0905 modulates the pharmacodynamic biomarker phosphorylated histone H3 (pHisH3) in tumor tissue. |
别名 | 6H-Pyrimido[5,4-d][1]benzazepine-6-thione, 2-[[5-[3-(dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)-;6H-Pyrimido[5,4-d][1]benzazepine-6-thione, 2-[[5-[3-(dimethylamino)propyl]-2-methyl-3-pyridinyl]amino]-5,7-dihydro-9-(trifluoromethyl)- |
MLN0905
MLN0905 (订货以英文为准)
编号:M126487
CAS号:1228960-69-7
分子式:C24H25F3N6S
分子量:486.56
货号 | 品牌 | 包装 | 目录价 | 您的价格 | 库存 | 数量 | 购买 |
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M126487-25mg | 阿拉丁 | 25mg | ¥2499.90 |
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M126487-2mg | 阿拉丁 | 2mg | ¥409.90 |
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M126487-5mg | 阿拉丁 | 5mg | ¥819.90 |
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M126487-1mg | 阿拉丁 | 1mg | ¥569.00 |
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M126487-10mg | 阿拉丁 | 10mg | ¥1299.90 |
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M126487-100mg | 阿拉丁 | 100mg | ¥6399.90 |
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M126487-50mg | 阿拉丁 | 50mg | ¥3999.90 |
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M126487-250mg | 阿拉丁 | 250mg | ¥12799.90 |
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产品名称 | MLN0905 |
中文名称 | MLN0905 |
CAS号 | 1228960-69-7 |
分子式(M.F.) | C24H25F3N6S |
分子量(M.W.) | 486.56 |
储存条件 | -20°C储存 |
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