| 溶解性 | Soluble in chloroform, methanol, DMSO (100 mg/ml), water (<1 mg/ml at 25 °C), and ethanol (100 mg/ml). |
| 存贮条件 | 储存温度-20°C |
| 应用 | An immunosuppresive inhibitor of FRAP (mTOR). |
| 产品介绍 | Everolimus (RAD001)是一种mTOR抑制剂，作用于FKBP12，IC50为1.6-2.4 nM。 |
| 备注 | Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM. |
| 生化机理 | Everolimus is a macrolide derived from rapamycin with immunosuppressant properties shown to inhibit cell proliferation induced by growth factors. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Studies indicate that everolimus is a mTOR (FRAP) inhibitor that displays high affinity toward the intracellular receptor FKBP12. Additionally, the Everolimus-FKBP12 complex decreases the activity of the S6K1 and 4EBP by binding to FRAP |
| 别名 | 依维莫司;RAD001; SDZ-RAD; Certican; Zortress; Afinitor;RAD 001;40-O-(2-Hydroxyethyl)rapamycin; 42-O-(2-Hydroxy)ethyl Rapamycin |
依维莫司
Everolimus （订货以英文为准）
编号：E125341
CAS号：159351-69-6
分子式：C53H83NO14
分子量：958.22
| 产品名称 | Everolimus |
| 中文名称 | 依维莫司 |
| CAS号 | 159351-69-6 |
| 分子式（M.F.） | C53H83NO14 |
| 分子量（M.W.） | 958.22 |
| 储存条件 | -20°C储存 |
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