| 敏感性 | 对热和空气敏感 |
| 溶解性 | Soluble in DMSO (25 mg/ml), ethanol (25 mg/ml)), chloroform, and acetone (easily soluble). |
| 存贮条件 | 储存温度 -20°C,充氩保存 |
| 应用 | An agonist displaying activity at retinoid receptors |
| 产品介绍 | Fenretinide (4-HPR)是合成的维甲酸衍生物，能结合维甲酸受体（RAR）。 |
| 生化机理 | 4-Hydroxyphenylretinamide (Fenretinide) is a synthetic retinoid analog of all trans retinoic acid, which displays antiproliferative effects on cultured human breast cancer cells. In addition, 4-Hydroxyphenylretinamide functions as a selective activator of RAR (retinoid receptors). Studies involving lymphoid and myeloid malignant cell lines indicate that 4-Hydroxyphenylretinamide can induce apoptosis and reduce cell growth. These studies suggest that 4-Hydroxyphenylretinamide and all trans retanoic acid may bind to two different receptors to induce apoptosis. |
| 别名 | 4-HPR;全反式-N-(4-羟苯基)维甲酸;维甲酸对羟基苯胺;芬维A胺;维甲酰酚胺;4-HPR; (4-Hydroxyphenyl)retinamide; N-(4-Hydroxyphenyl)retinamide;all-trans-N-(4-Hydroxyphenyl)retinamide;Retinoic acid p-hydroxyanilide;4-Hydroxyphenylretinamide |
全反式-N-(4-羟苯基)维甲酸
Fenretinide （订货以英文为准）
编号：F126912
CAS号：65646-68-6
分子式：C26H33NO2
分子量：391.55
| 产品名称 | Fenretinide |
| 中文名称 | 全反式-N-(4-羟苯基)维甲酸 |
| CAS号 | 65646-68-6 |
| MDL编码 | MFCD00792674 |
| 分子式（M.F.） | C26H33NO2 |
| 分子量（M.W.） | 391.55 |
| 储存条件 | -20°C储存;充氩 |
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