存贮条件 | 储存温度2-8℃ |
密度 | 1.1300 |
应用 | Aprotinin is largely used as an inhibitor of trypsin. |
产品介绍 | Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes and blocks the active sites of serine protease enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3 (optimum pH 5-7); effective concentration is equimolar with protease. Used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones. |
备注 | 另一个常用的活性单位是 KIU(激肽释放酶抑制剂单位)。1 TIU ~ 1,300 KIU。 |
生化机理 | Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. |
别名 | 重组胰蛋白酶抑制剂;抑肽酶(牛肺);抗蛋白酶肽(牛肺);蛋白酶抑制剂;抑肽酶;Trasylol 胰蛋白酶抑制剂(碱性);Trypsin inhibitor (basic) |
抑肽酶 来源于牛肺
Aprotinin from bovine lung (订货以英文为准)
编号:A105534
CAS号:9087-70-1
分子式:C284H432N84O79S7
分子量:6511.44
产品名称 | Aprotinin from bovine lung |
中文名称 | 抑肽酶 来源于牛肺 |
CAS号 | 9087-70-1 |
分子式(M.F.) | C284H432N84O79S7 |
分子量(M.W.) | 6511.44 |
储存条件 | 2-8°C储存 |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 3 |
安全声明(欧洲) | 22,24/25 |
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