6,7-二甲氧基香豆素

6,7-Dimethoxycoumarin (订货以英文为准)

编号:D101246
CAS号:120-08-1
分子式:C11H10O4
分子量:206.19
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D101246-250mg 阿拉丁 250mg ¥500.90
D101246-1g 阿拉丁 1g ¥1499.90
D101246-25g 阿拉丁 25g ¥14849.90
D101246-5g 阿拉丁 5g ¥4948.90
产品名称 6,7-Dimethoxycoumarin
中文名称 6,7-二甲氧基香豆素
CAS号 120-08-1
分子式(M.F.) C11H10O4
分子量(M.W.) 206.19
熔点143-145°C
溶解性Soluble in DMSO (15 mg/ml), and water (partly miscible).
密度1.2480
应用An agent that can up-regulate the expression and activate CAR
产品介绍Scoparone is a compound found in the herb, Yin Chin, that can up-regulate the expression and activate the CAR (constitutive androstane receptor) found in the liver. It has been shown to clear the accumulation of bilirubin by the activation of CAR in neonatal jaundice. Other studies show that scaparone inhibits lipopolysaccharide (LPS)-induced tissue factor (TF) expression in HUVECs and that it acts as an anti-inflammatory compound. TCPOBOP also transactivates CAR, however, scoparone can activate murine and human CAR. Scaparone can increase dopamine release by synapsin I phosphorylation through activation of PKA and CaMKII? in PC12 cells. It can also activate neurite outgrowth and improve dopamine biosynthesis in PC12 cells.
别名蒿属香豆素;Scoparone;6,7-Dimethylesculetin;6,7-Dimethoxy-2H-chromen-2-one;6,7-Dimethoxy-2-benzopyrone
搜索质检报告(COA)
搜索MSDS
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