| 溶解性 | Soluble in water. Also soluble in methanol, DMSO (33 mg/ml) and ethanol (<1 mg/ml). |
| 应用 | 2-Mercaptoethanesulfonic acid sodium salt (Coenzyme M sodium salt, MESNA) is used as an antioxidant and cytoprotective agent in a wide variety of applications from protection from toxicity of therapeutic agents, such as cyclophosphamide to prevention from brain injury damage. |
| 生化机理 | Description:IC50 Value: 182mM (decreased superoxide anion production stimulated with PMA (tetradecanoylphorbol acetate) in PMN in-vitro); 70mM (inhibited H2O2 production) [3]2-mercaptoethane sulfonate (MESNA), is a synthetic small molecule, widely used as a systemic protective agent against chemotherapy toxicity, but is primarily used to reduce hemorrhagic cystitis induced by cyclophosphamide[1].in vitro: MESNA had no effect on the qualitative and quantitative characteristics of the indicated processes in both the types of the doxorubicin sensitive cells. The combined use of doxorubicin and phosphamide or cyclophosphane the use of MESNA for lowering the urotoxic action of oxazophosphorines had no effect on the biological efficacy of doxorubicin [4].in vivo: AMH-positive follicles were significantly decreased after cisplatin administration, which was significantly reversed when mesna was co-administered with cisplatin. The end product of lipid pe |
| 别名 | 美司那;2-巯基乙基磺酸钠盐;2-巯基乙磺酸钠盐;HS-CoM Na;MESNA;辅酶 M 钠盐 ;Mesna;2-Mercaptoethanesulfonic acid sodium salt |
2-巯基乙烷磺酸钠
Sodium 2-mercaptoethanesulfonate （订货以英文为准）
编号：S123250
CAS号：19767-45-4
分子式：C2H5NAO3S2
分子量：164.17
| 产品名称 | Sodium 2-mercaptoethanesulfonate |
| 中文名称 | 2-巯基乙烷磺酸钠 |
| CAS号 | 19767-45-4 |
| MDL编码 | MFCD00007535 |
| 分子式（M.F.） | C2H5NAO3S2 |
| 分子量（M.W.） | 164.17 |
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