| 存贮条件 | 储存温度2-8°C |
| 密度 | 1.8700 |
| 产品介绍 | Chaetocin, a natural product originally produced by Chaetomium species, is shown to have apoptotic effects on some cancer cells. Mechanistic studies show that chaetocin is taken up in the cells by a process that requires intact/unreduced disulfides for uptake. Once inside, this compound imposes oxidative stress and consequent apoptosis induction. Other studies have shown chaetocin to reduce lysine-specific histone methyltransferase effects of SUV39H, which play a key role in maintaining stable gene expression patterns during embryonic development and cellular differentiation. Additionally, this agent is reported to cause profound chromatin reorganization in fibroblast nuclei by inducing chromatin condensation/clustering. Consequentially, chaetocin impairs Trx (thioredoxin) systems, which are essential for deoxynucleotide synthesis and involved in a broad range of cellular functions. Chaetocin is an inhibitor of G9a, SUV39H1 and TrxR1. |
| 别名 | ; |
毛壳素
Chaetocin from Chaetomium minutum （订货以英文为准）
编号：C102377
CAS号：28097-03-2
分子式：C30H28N6O6S4
分子量：696.84
| 产品名称 | Chaetocin from Chaetomium minutum |
| 中文名称 | 毛壳素 |
| CAS号 | 28097-03-2 |
| 分子式（M.F.） | C30H28N6O6S4 |
| 分子量（M.W.） | 696.84 |
| 储存条件 | 2-8°C储存 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Danger |
| 危害声明 | H300,H361 |
| 警示性声明 | P264,P281,P301+P310 |
| 个人防护设备 | Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges |
| RTECS | GZ4850000 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | 25,63 |
| 安全声明（欧洲） | 36/37,45 |
| 危害码（欧洲） | T |
| UN代码 | 1544 |
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