溶解性 | DMSO 83 mg/mL Water 2 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
备注 | OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). |
生化机理 | OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. |
别名 | 2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride;2-(4-(3-ethynylphenylamino)-7-(2-methoxyethoxy)quinazolin-6-yloxy)ethanol hydrochloride |
去甲厄洛替尼盐酸盐
OSI-420 (订货以英文为准)
编号:O125033
CAS号:183320-51-6
分子式:C21H21N3O4.HCL
分子量:415.87
产品名称 | OSI-420 |
中文名称 | 去甲厄洛替尼盐酸盐 |
CAS号 | 183320-51-6 |
分子式(M.F.) | C21H21N3O4.HCL |
分子量(M.W.) | 415.87 |
储存条件 | -20°C储存 |
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