敏感性 | 易吸湿 |
溶解性 | Soluble in water (30 mg/ml), DMSO (100 mM), methanol, and ethanol (25 mM). |
存贮条件 | 储存温度2-8℃ |
应用 | An inhibitor of HMGCR (HMG-CoA reductase). |
产品介绍 | Fluvastatin Sodium抑制HMG-CoA reductase(HMG-CoA还原酶)活性,IC50为8 nM。 |
备注 | Fluvastatin Sodium inhibits HMG-CoA reductase activity with IC50 of 8 nM. |
生化机理 | Fluvastatin, Sodium Salt is a synthetic inhibitor of HMGCR (HMG-CoA reductase) (IC50 = 40-100 nM for human liver microsomes) that acts as an anti-hypercholesterolemic compound and as an antioxidant. Fluvastatin also inhibits induction of the LDL receptor on HepG2 cells at a concentration of 0.1-1.0 μM. Research shows that fluvastatin can inhibit the formation of TBA-reactive substances in Fe(II)-supported peroxidation of liposomes (IC50 = 12 μM). |
别名 | 氟伐他汀钠; [R*,S*-(E)]-(+/-)-7-[3-(4-氟苯基)-1-(1-甲基乙基)-1-氢-吲哚-2-基]-3,5-二羟基庚-6-烯酸钠;Vastin;Leschol sodium;(3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt |
氟伐他汀钠 水合物
Fluvastatin Sodium (订货以英文为准)
编号:F129852
CAS号:93957-55-2
分子式:C24H26FNNAO4
分子量:434.46
产品名称 | Fluvastatin Sodium |
中文名称 | 氟伐他汀钠 水合物 |
CAS号 | 93957-55-2 |
分子式(M.F.) | C24H26FNNAO4 |
分子量(M.W.) | 434.46 |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs09.jpg |
信号词 | Warning |
危害声明 | H319-H410 |
警示性声明 | P273-P305 + P351 + P338-P501 |
个人防护设备 | Eyeshields, Gloves |
WGK德国 | 3 |
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