熔点 | 143-148℃ |
敏感性 | 对光敏感 |
溶解性 | Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water. |
应用 | A potent suicide inhibitor of cytochrome P-450. |
生化机理 | 8-Methoxypsoralen is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrome P-450 2B1). 8-Methoxypsoralen has been shown to completely inhibit the metabolism of nicotine in vitro. The compound has been observed to inhibit the metabolism of theophylline,caffeine,hexobarbital and phenytoin. |
别名 | 花椒毒素;甲氧基补骨脂素;甲氧沙林;8-MOP;9-甲氧基呋喃并[3,2-g][1]苯并吡喃-7-酮;花椒毒内酯8-MOP;Ammoidin;Methoxsalen;Xanthotoxin;9-Methoxyfuro[3,2-g][1]benzopyran-7-one |
8-甲氧基补骨脂素
8-Methoxypsoralen (订货以英文为准)
编号:M137749
CAS号:298-81-7
分子式:C12H8O4
分子量:216.19
产品名称 | 8-Methoxypsoralen |
中文名称 | 8-甲氧基补骨脂素 |
CAS号 | 298-81-7 |
分子式(M.F.) | C12H8O4 |
分子量(M.W.) | 216.19 |
Reaxys-RN | 116295 |
闪点(摄氏) | 71°C(lit.) |
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