1. 首页
  2. 产品目录

维兰特罗

Vilanterol （订货以英文为准）

编号：V126837
CAS号：503068-34-6
分子式：C24H33CL2NO5
分子量：486.43
货号 品牌 包装 目录价 您的价格 库存 数量 购买
V126837-5mg 阿拉丁 5mg ¥1441.90
请登录
V126837-25mg 阿拉丁 25mg ¥4119.90
请登录
V126837-50mg 阿拉丁 50mg ¥5767.90
请登录
V126837-500mg 阿拉丁 500mg ¥7982.90
请登录
产品名称 Vilanterol
中文名称 维兰特罗
CAS号 503068-34-6
分子式（M.F.） C24H33CL2NO5
分子量（M.W.） 486.43
储存条件 -20°C储存
溶解性25°C: DMSO
存贮条件储存温度-20°C
产品介绍Vilanterol (GW642444; GW 642444X)是吸入型长效β2激动剂。
生化机理in vitro:Vilanterol displayed a subnanomolar affinity for the β(2)-AR that was comparable with that of salmeterol but higher than olodaterol, formoterol, and indacaterol. In cAMP functional activity studies, vilanterol demonstrated similar selectivity as salmeterol for β(2)- over β(1)-AR and β(3)-AR, but a significantly improved selectivity profile than formoterol and indacaterol. Vilanterolalso showed a level of intrinsic efficacy that was comparable to indacaterol but significantly greater than that of salmeterol。 in vivo: The combination of FF/VI at a strength of 100/25 μg significantly (p < 0.001) improved wm FEV1 (173 ml) and trough FEV1 (115 ml) vs. placebo. Similar effects were observed with FF/VI 50/25 μg. VI 25 μg over 24 weeks improved lung function vs. placebo significantly for wm FEV1 (103 ml, p < 0.001) and trough FEV1 (67 ml, p = 0.017)
别名维兰特罗;GW 642444X;GW 642444;GW642444X;GW642444;GW-642444X;GW-642444；4-[(R)-2-[[6-[2-(2,6-Dichlorobenzyloxy)ethoxy]hexyl]amino]-1-hydroxyethyl]-2-hydroxymethylphenol
搜索质检报告(COA)
搜索MSDS
相关产品