| 溶解性 | DMSO 89 mg/mL Water <1 mg/mL Ethanol 7 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 备注 | Crenolanib (CP-868596) is a potent and selective inhibitor of PDGFRα/β with Kd of 2.1 nM/3.2 nM, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, |
| 生化机理 | Crenolanib (CP-868569) is a highly selective and potent PDGFR-α inhibitor with IC50 of 0.9 and 1.8 nM against PDGFRα and PDGFRβ, respectively. In addition,Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase with an IC50 of 1 nM. |
| 别名 | 1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine;1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine |
克莱拉尼
Crenolanib (CP-868596) （订货以英文为准）
编号：C127776
CAS号：670220-88-9
分子式：C26H29N5O2
分子量：443.54
| 产品名称 | Crenolanib (CP-868596) |
| 中文名称 | 克莱拉尼 |
| CAS号 | 670220-88-9 |
| 分子式（M.F.） | C26H29N5O2 |
| 分子量（M.W.） | 443.54 |
| 储存条件 | -20°C储存 |
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