| 熔点 | 292 °C |
| 旋光率 | +58.0 to +65.0 deg(C=1, Pyridine) |
| 敏感性 | 对空气敏感 |
| 存贮条件 | 存储温度2-8℃;充氩保存 |
| 密度 | 1.0900 |
| 应用 | An anti-angiogenic and anti-proliferative agent |
| 产品介绍 | 存在于天然植物中的一种三萜类化合物。不溶于水，溶于2%酒精的NaOH，溶于热冰醋酸，中度溶于丙酮，微溶于醇、醚、氯仿和二硫化碳。 |
| 生化机理 | Ursolic Acid, a naturally occurring triterpenoid, has been noted to demonstrate anti-angiogenic and anti-proliferative properties. Mechanistic studies suggest that this compound down-regulates MMP-2 and uPA expression in cells via inhibition of Akt, JNK, mammalian target of Rapamycin phosphorylation, and levels of NFκB protein in the nucleus. Other experiments have shown that Ursolic Acid may improve blood glucose, glucose tolerance, insulin tolerance, glycosylated hemoglobin, and plasma leptin levels in diabetic murine models. Additionally, this agent displays a capacity to induce cell cycle arrest and apoptosis through activation of p53 pathway and Bax protein, as well as down-regulation of Bcl-2. |
| 别名 | 乌苏酸;乌索酸;3-羟基-(3β)-乌索-12-烯-28-酸;3β-Hydroxy-12-ursen-28-ic acid |
熊果酸
Ursolic acid （订货以英文为准）
编号：U118635
CAS号：77-52-1
分子式：C30H48O3
分子量：456.70
| 产品名称 | Ursolic acid |
| 中文名称 | 熊果酸 |
| CAS号 | 77-52-1 |
| 分子式（M.F.） | C30H48O3 |
| 分子量（M.W.） | 456.70 |
| 储存条件 | 2-8°C储存;充氩 |
| Reaxys-RN | 1811476 |
| RTECS | JR1305000 |
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