枸橼酸西地那非

Sildenafil Citrate (订货以英文为准)

编号:S129663
CAS号:171599-83-0
分子式:C28H38N6O11S
分子量:666.70
货号 品牌 包装 目录价 您的价格 库存 数量 购买
S129663-100mg 阿拉丁 100mg ¥30.90
S129663-500mg 阿拉丁 500mg ¥82.00
S129663-25mg 阿拉丁 25mg ¥29.90
S129663-1g 阿拉丁 1g ¥31.90
S129663-5g 阿拉丁 5g ¥52.90
S129663-25g 阿拉丁 25g ¥130.90
S129663-100g 阿拉丁 100g ¥492.90
产品名称 Sildenafil Citrate
中文名称 枸橼酸西地那非
CAS号 171599-83-0
分子式(M.F.) C28H38N6O11S
分子量(M.W.) 666.70
熔点185-187 °C
溶解性Soluble in water (3.5 mg/ml), DMSO (23 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), methanol, and DMF (~14 mg/ml).
应用An orally active selective type 5 cGMP phosphodiesterase inhibitor.
产品介绍Sildenafil Citrate是一种治疗勃起功能障碍和肺动脉高压(PAH)的药剂。
合法信息Sold for only research purposes
备注Sildenafil citrate is an agent used to treat erectile dysfunction and pulmonary arterial hypertension (PAH).
生化机理Sildenafil, Citrate is a citrate form of Sildenafil. Sildenafil is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism. In vitro, increases NO2-dependent relaxation of human corpus cavernosum.
别名枸橼酸西地那非; 1-[4-乙氧基-3-[5-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑并[4,3-d]嘧啶)]苯磺酰]-4-甲基哌嗪枸橼酸盐;1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate salt; 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[5,4-e]pyrimidin-7-one citrate salt; Revatio citrate; UK-92480 citrate; Viagra citrate
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