熔点 | 185-187 °C |
溶解性 | Soluble in water (3.5 mg/ml), DMSO (23 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), methanol, and DMF (~14 mg/ml). |
应用 | An orally active selective type 5 cGMP phosphodiesterase inhibitor. |
产品介绍 | Sildenafil Citrate是一种治疗勃起功能障碍和肺动脉高压(PAH)的药剂。 |
合法信息 | Sold for only research purposes |
备注 | Sildenafil citrate is an agent used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). |
生化机理 | Sildenafil, Citrate is a citrate form of Sildenafil. Sildenafil is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism. In vitro, increases NO2-dependent relaxation of human corpus cavernosum. |
别名 | 枸橼酸西地那非; 1-[4-乙氧基-3-[5-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑并[4,3-d]嘧啶)]苯磺酰]-4-甲基哌嗪枸橼酸盐;1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate salt; 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[5,4-e]pyrimidin-7-one citrate salt; Revatio citrate; UK-92480 citrate; Viagra citrate |
枸橼酸西地那非
Sildenafil Citrate (订货以英文为准)
编号:S129663
CAS号:171599-83-0
分子式:C28H38N6O11S
分子量:666.70
产品名称 | Sildenafil Citrate |
中文名称 | 枸橼酸西地那非 |
CAS号 | 171599-83-0 |
分子式(M.F.) | C28H38N6O11S |
分子量(M.W.) | 666.70 |
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