别名 | 2-亚硝基-5-二乙基氨基苯酚盐酸盐;2-Nitroso-5-Diethylaminophenol Hydrochloride ;5-(Diethylamino)-2-Nitrosophenol Hydrochloride; Ccris 4614 |
5-二乙氨基-2-亚硝基苯酚盐酸盐
5-Diethylamino-2-nitrosophenol Hydrochloride (订货以英文为准)
编号:D155066
CAS号:25953-06-4
分子式:C10H14N2O2.HCL
分子量:230.69
产品名称 | 5-Diethylamino-2-nitrosophenol Hydrochloride |
中文名称 | 5-二乙氨基-2-亚硝基苯酚盐酸盐 |
CAS号 | 25953-06-4 |
分子式(M.F.) | C10H14N2O2.HCL |
分子量(M.W.) | 230.69 |
Reaxys-RN | 4419813 |
信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
WGK德国 | 3 |
技术规格
Background: | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription. |
Applications: | WB, IHC, IF |
Name of antibody: | NFKBIA (Phospho-Ser32/Ser36) |
Immunogen: | Synthetic peptide of human NFKBIA (Phospho-Ser32/Ser36) |
Full name: | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (Phospho-Ser32/Ser36) |
Synonyms: | IKBA; MAD-3; NFKBI |
SwissProt: | P25963 |
IHC positive control: | Human breast carcinoma |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 39 kDa |
WB Positive control: | Hela cells untreated or treated with TNF |
WB Recommended dilution: | 500-1000 |
Positive control: | Hela cells |
Recommended dilution: | 100-200 |
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