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TAK-700 (Orteronel),抑制剂

TAK-700 (Orteronel) （订货以英文为准）

编号：T126788
CAS号：426219-18-3
分子式：C18H17N3O2
分子量：307.35
货号 品牌 包装 目录价 您的价格 库存 数量 购买
T126788-5mg 阿拉丁 5mg ¥968.90
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T126788-25mg 阿拉丁 25mg ¥2574.90
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T126788-1mg 阿拉丁 1mg ¥273.90
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T126788-10mg 阿拉丁 10mg ¥1441.90
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T126788-50mg 阿拉丁 50mg ¥4016.90
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产品名称 TAK-700 (Orteronel)
中文名称 TAK-700 (Orteronel),抑制剂
CAS号 426219-18-3
分子式（M.F.） C18H17N3O2
分子量（M.W.） 307.35
储存条件 -20°C储存
溶解性DMSO 61 mg/mL Water <1 mg/mL Ethanol 8 mg/mL
存贮条件储存温度-20°C
备注TAK-700 (Orteronel) is a potent and highly selective human 17,20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.
生化机理TAK-700 is an oral, selective, non-steroidal androgen synthesis inhibitor of the 17,20 lyase, which is a key enzyme in the production of steroidal hormones. In preclinical studies, TAK-700 has been shown to bind to and inhibit the enzyme 17,20 lygase in both the testes and adrenal glands. TAK-700 is currently under clinical Phase III studies.
别名(S)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-e]imidazol-7-yl)-N-methyl-2-naphthamide;(S)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-e]imidazol-7-yl)-N-methyl-2-naphthamide
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H315-H319-H335
警示性声明P261-P305 + P351 + P338
个人防护设备dust mask type N95 (US), Eyeshields, Gloves
RTECSUY5749237
WGK德国3
搜索质检报告(COA)
搜索MSDS
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