| 别名 | ;['3,6-Bis(4-pyridyl)-1,2,4,5-tetrazine'] |
3,6-二(4-吡啶基)-1,2,4,5-四嗪
3,6-Di(4-pyridyl)-1,2,4,5-tetrazine （订货以英文为准）
编号：D155261
CAS号：57654-36-1
分子式：C12H8N6
分子量：236.24
| 产品名称 | 3,6-Di(4-pyridyl)-1,2,4,5-tetrazine |
| 中文名称 | 3,6-二(4-吡啶基)-1,2,4,5-四嗪 |
| CAS号 | 57654-36-1 |
| MDL编码 | D155261 |
| 分子式（M.F.） | C12H8N6 |
| 分子量（M.W.） | 236.24 |
| Reaxys-RN | 113297 |
| RTECS | DW1758000 |
技术规格
| Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |
| Applications: | WB, IHC |
| Name of antibody: | HDAC5 |
| Immunogen: | Synthetic peptide of human HDAC5(Ab-498) |
| Full name: | histone deacetylase 5 |
| Synonyms： | HD5; NY-CO-9 |
| SwissProt: | Q9UQL6 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 122 kDa |
| WB Positive control: | 293 and HepG2 cells |
| WB Recommended dilution: | 500-1000 |
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