| 熔点 | 256°C |
| 溶解性 | DMSO : 150 mg/mL (842.03 mM; Need ultrasonic and warming) |
| 存贮条件 | 储存温度-20°C |
| 生化机理 | Daphnetin is an inhibitor of protein kinases. It is an active lactone present in plants such as Daphne Korean Nakai, and Thymelaeaceae Daphne. It serves as as analgesic, antiviral and antibacterial agent. 7,8-Dihydroxycoumarinan is found to induce tumor apoptosis via a number of signalling pathways. Thus, it is believed to exhibit antitumor effects. 7,8-Dihydroxycoumarinan might also be useful in treating lung carcinoma.It is also known to be used in treating coagulation disorders and rheumatoid arthritis. 7,8-Dihydroxycoumarinan is known to induce neurite growth and lengthen neuronal survival. It helps in clearing substances inducing necrosis, maintains water-electrolytes balance and energy metabolism. 7,8-Dihydroxycoumarinan is involved in the generation of neurotrophic factor and helps in restoring neuron function. |
| 别名 | 瑞香素;7,8-Dihydroxycoumarin；Daphnetol；Ruixiangsu |
瑞香素
Daphnetin （订货以英文为准）
编号：D155111
CAS号：486-35-1
分子式：C9H6O4
分子量：178.14
| 产品名称 | Daphnetin |
| 中文名称 | 瑞香素 |
| CAS号 | 486-35-1 |
| 分子式（M.F.） | C9H6O4 |
| 分子量（M.W.） | 178.14 |
| 储存条件 | -20°C储存 |
| Reaxys-RN | 102391 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs02.jpg,https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Danger |
| 危害声明 | H225,H319,H335 |
| 警示性声明 | P210,P261,P305+P351+P338 |
| 个人防护设备 | Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter |
| RTECS | LU5950000 |
| WGK德国 | 1 |
| 闪点（摄氏） | -17℃ |
| 风险声明 (欧洲) | R11;R19;R36/37 |
| 安全声明（欧洲） | S16;S33 |
| 危害码（欧洲） | F,Xi |
| 是否危化品 | 一般危化品 |
| UN代码 | 2056 |
技术规格
| Background: | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear |
| Applications: | WB, IHC |
| Name of antibody: | STMN1 (Phospho-Ser16) |
| Immunogen: | Synthetic peptide of human STMN1 (Phospho-Ser16) |
| Full name: | stathmin 1 (Phospho-Ser16) |
| Synonyms： | Lag; SMN; OP18; PP17; PP19; PR22; LAP18; C1orf215 |
| SwissProt: | P16949 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 17 kDa |
| WB Positive control: | 293 cells treated with Nocodazol |
| WB Recommended dilution: | 500-1000 |
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