| 溶解性 | 25°C: DMSO |
| 存贮条件 | 储存温度-20°C |
| 应用 | TDZD-8 has been used to study the role of GSK-3 in maintaining MLL leukemia stem cell transcriptional program;TDZD-8 has also been used to analyze its effect on neural functions of the mouse olfactory bulb. |
| 产品介绍 | TDZD-8(NP 01139)是thiadiazolidinone的衍生物，是非ATP竞争性GSK-3β抑制剂，IC50为2 μM，对Cdk-1/cyclin B，CK-II，PKA和PKC无活性。 |
| 生化机理 | TDZD-8 is a selective inhibitor of GSK-3, a thiadiazolidinone derivative, non-ATP competitive inhibitor of GSK-3β (IC50 = 2 μM). It does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. TDZD-8 has been proposed to bind to the kinase site of GSK-3β. |
| 别名 | TDZD 8;TDZD8;NP 01139;4-苄基-2-甲基-1,2,4-噻二唑烷-3,5-二酮;TDZD 8;TDZD8;GSK-3β Inhibitor I;NP 01139;4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione |
4-苯甲基-2-甲基-1,2,4-噻二唑烷-3,5-二酮
TDZD-8 （订货以英文为准）
编号：T126722
CAS号：327036-89-5
分子式：C10H10N2O2S
分子量：222.26
| 产品名称 | TDZD-8 |
| 中文名称 | 4-苯甲基-2-甲基-1,2,4-噻二唑烷-3,5-二酮 |
| CAS号 | 327036-89-5 |
| MDL编码 | MFCD04973552 |
| 分子式（M.F.） | C10H10N2O2S |
| 分子量（M.W.） | 222.26 |
| 储存条件 | -20°C储存 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg |
| 信号词 | Danger |
| 危害声明 | H301 |
| 警示性声明 | P301 + P310 |
| WGK德国 | 3 |
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