溶解性 | Soluble in water (<1 mg/ml) at 25 °C, DMSO (13 mg/ml) at 25 °C, and ethanol (<1 mg/ml) at 25 °C. |
存贮条件 | 储存温度-20°C |
应用 | A selective Chk1 inhibitor. |
产品介绍 | Y2603618是一种选择性Chk1抑制剂,具有潜在的抗肿瘤活性。Phase 2。 |
备注 | LY2603618 is a selective Chk1 inhibitor with potential anti-tumor activity. |
生化机理 | LY2603618 (IC-83) is a very selective checkpoint kinase 1 (Chk1) inhibitor with the potential for antitumor effects. Chk1 is an ATP-dependent serine-threonine kinase that is very important to the checkpoint monitoring system of DNA replication. |
别名 | N-[5-溴-4-甲基-2-[(2S)-2-吗啉甲氧基]苯基]-N'-(5-甲基-2-吡嗪基)脲;IC-83; LY 2603618; LY-2603618;N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)urea;(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea |
LY2603618,Chk1抑制剂
LY2603618 (订货以英文为准)
编号:L126277
CAS号:911222-45-2
分子式:C18H22BRN5O3
分子量:436.30
产品名称 | LY2603618 |
中文名称 | LY2603618,Chk1抑制剂 |
CAS号 | 911222-45-2 |
分子式(M.F.) | C18H22BRN5O3 |
分子量(M.W.) | 436.30 |
储存条件 | -20°C储存 |
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