(R)-(-)-布洛芬

(R)-(-)-Ibuprofen (订货以英文为准)

编号:L126048
CAS号:51146-57-7
分子式:C13H18O2
分子量:206.28
货号 品牌 包装 目录价 您的价格 库存 数量 购买
L126048-250mg 阿拉丁 250mg ¥376.90
L126048-1g 阿拉丁 1g ¥1303.90
L126048-50mg 阿拉丁 50mg ¥81.90
L126048-5g 阿拉丁 5g ¥4604.90
L126048-100mg 阿拉丁 100mg ¥94.90
产品名称 (R)-(-)-Ibuprofen
中文名称 (R)-(-)-布洛芬
CAS号 51146-57-7
分子式(M.F.) C13H18O2
分子量(M.W.) 206.28
储存条件 2-8°C储存
沸点319.64 °C/760 mmHg
熔点50.5-52.5 °C
折光率1.52
溶解性Soluble in methanol, 0.1 M NaOH, dichloromethane, and ethyl acetate.
密度1.0300
应用An inhibitor of Cox-1 and Cox-2.
产品介绍(R)-Ibuprofen是ibuprofen的低活性对映体。
生化机理(R)-Ibuprofen, a nonsteroidal antiinflammatory, is the less active enantiomer of ibuprofen, an inhibitor of Cox-1 and Cox-2. Most of the activity resides in (S)-ibuprofen. It has been observed that the inversion of R(-)-ibuprofen to the S(+) antipode occurs in rat liver but not in either serosal or mucosal sides of the small intestine. (R)-Ibuprofen’s presence can be detected in urine through mass chromatography. A liquid-chromatographic assay has been used to study the pharmacokinetics of the (S)- and (R)-Ibuprofen forms in plasma.
别名(R)-布洛芬;(R)-Ibuprofen;L-Ibuprofen;(alphaR)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid; R-(-)-p-Isobutylhydratropic acid; R-(-)-p-Isobutylhydratropic acid
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