| 熔点 | 158°C |
| 存贮条件 | 储存温度2-8°C |
| 应用 | Diclofenac (双氯芬酸) 是COX抑制剂，对绵羊的COX-1和-2的IC50分别为60和220 nM。 |
| 产品介绍 | Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. The primary mechanism responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diclofenac has a low to moderate preference to block the COX2-isoenzyme and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin. |
| 别名 | 双氯芬酸;2-(2,6-二氯苯氨基)苯乙酸;2-[(2,6-二氯苯基)氨基]-苯乙酸;奥尔芬;2-(2,6-Dichloroanilino)phenylacetic Acid |
2-(2,6-二氯苯氨基)苯乙酸
Diclofenac （订货以英文为准）
编号：D155733
CAS号：15307-86-5
分子式：C14H11CL2NO2
分子量：296.15
| 产品名称 | Diclofenac |
| 中文名称 | 2-(2,6-二氯苯氨基)苯乙酸 |
| CAS号 | 15307-86-5 |
| 分子式（M.F.） | C14H11CL2NO2 |
| 分子量（M.W.） | 296.15 |
| 储存条件 | 2-8°C储存 |
| Merck Index | 2801 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Warning |
| 危害声明 | H315,H319 |
| 警示性声明 | P305+P351+P338 |
| 个人防护设备 | dust mask type N95 (US),Eyeshields,Gloves |
| RTECS | DJ3100040 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | 36/38 |
| 安全声明（欧洲） | 24,26 |
| 危害码（欧洲） | Xi |
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