| 熔点 | 270°C |
| 敏感性 | 对湿度敏感&对光敏感 |
| 溶解性 | Soluble in DMSO (25 mg/ml), water (0.25 g/100ml) at 25 °C, ethanol (<1 mg/ml) at 25 °C, and DMF (16 mg/ml) |
| 存贮条件 | 充氩保存 |
| 密度 | 3.7000 |
| 应用 | cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery.cis-Diammineplatinum(II) dichloride has been used: · in cell viability measurement in cochlear explants· in the inhibition of cell proliferation and chemosensitivity in ovarian cancer cell lines· in MTT [3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide] cell viability assay in oral squamous cell carcinoma |
| 产品介绍 | 微溶于水，易溶于二甲基甲酰胺。在水溶液中可逐渐转化成反式和水解。 |
| 生化机理 | Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links. Potent chemoimmunotherapeutic drug; stimulates the immune responses by activating macrophages and other cells of the immune system. Cisplatin-treated macrophages show increased antigen presentation function in vitro. Treatment increased cellular NF-κB content and translocation in macrophages. Cisplatin effects are regulated by kinases, phosphatases, and Ca2+/calmodulin. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand crosslinks. Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links. |
| 别名 | 顺双氯双氨络铂，氯氨铂，顺二氯二氨基铂;顺式-二胺二氯铂;顺-二胺二氯铂(II);顺氯氨铂;cis-Dichlorodiammine platinum(II); cis-Platinum(II) diammine dichloride; cis-Diammineplatinum(II) dichloride ; Cisplatin |
顺铂
cis-Diammineplatinum dichloride （订货以英文为准）
编号：D109812
CAS号：15663-27-1
分子式：CL2H6N2PT
分子量：300.05
| 产品名称 | cis-Diammineplatinum dichloride |
| 中文名称 | 顺铂 |
| CAS号 | 15663-27-1 |
| 分子式（M.F.） | CL2H6N2PT |
| 分子量（M.W.） | 300.05 |
| 储存条件 | 避光;充氩 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs05.jpg,https://www.aladdin-e.com/images/ghs/ghs06.jpg |
| 信号词 | Danger |
| 危害声明 | H301,H314,H317 |
| 警示性声明 | P280,P301+P310,P305+P351+P338 |
| 个人防护设备 | Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges |
| RTECS | TP2275500 |
| WGK德国 | 3 |
| 风险声明 (欧洲) | R22;R34;R42/43; |
| 安全声明（欧洲） | 26,27,36/37/39,45 |
| 危害码（欧洲） | C |
| UN代码 | 2923 |
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