| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | NBD-556是CD4的小分子模拟物，能识别HIV-1包膜蛋白gp120。 |
| 生化机理 | NBD-556 N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analogs as a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors that block the gp120–CD4 interaction. Human immunodeficiency virus (HIV-1) interaction with the primary receptor, CD4, induces conformational changes in the viral envelope glycoproteins that allow binding to the CCR5 second receptor and virus entry into the host cell. The small molecule NBD-556 mimics CD4 by binding the gp120 exterior envelope glycoprotein, moderately inhibiting virus entry into CD4-expressing target cells and enhancing CCR5 binding and virus entry into CCR5-expressing cells lacking CD4. |
| 别名 | NBD 556;NBD556;N-(4-氯苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺;N1-(4-氯苯基)-N2-(2,2,6,6-四甲基-4-哌啶基)乙二酰胺;N1-(4-氯苯基)-N2-(2,2,6,6-四甲基哌啶-4-基)草酰胺;NBD 556;NBD556;N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide;N-(4-Chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide;N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide |
NBD-556,CD4类似物
NBD-556 （订货以英文为准）
编号：N125945
CAS号：333353-44-9
分子式：C17H24CLN3O2
分子量：337.84
| 产品名称 | NBD-556 |
| 中文名称 | NBD-556,CD4类似物 |
| CAS号 | 333353-44-9 |
| 分子式（M.F.） | C17H24CLN3O2 |
| 分子量（M.W.） | 337.84 |
| 储存条件 | -20°C储存 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg |
| 信号词 | Danger |
| 危害声明 | H301-H315-H319-H335 |
| 警示性声明 | P261-P301 + P310-P305 + P351 + P338 |
| 个人防护设备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| RTECS | UE7570000 |
| WGK德国 | 3 |
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