| 溶解性 | DMSO ≥86mg/mL Water <1.2mg/mL Ethanol ≥85mg/mL |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | An HIV-1 integrase inhibitor |
| 产品介绍 | Elvitegravir (GS-9137, JTK-303)是人免疫缺陷病毒整合酶抑制剂，作用于HIV-1 IIIB， HIV-2 EHO和HIV-2 ROD时，IC50分别为0.7，2.8和1.4 nM。 |
| 备注 | Elvitegravir (EVG, JTK-303/GS-9137) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively. |
| 生化机理 | Elvitegravir is an inhibitor of HIV-1 integrase which is responsible for the strand-transfer step of integration. Studies indicate that Elvitegravir is effective against HIV-1 strains that are resistant to other agents such as nucleotide reverse-transcriptase inhibitors (NRTIs), nonnucleoside reverse-transcriptase inhibitors (NNRTIs), and protease inhibitors (PIs), as a result of Elvitegravir's ability to block the function of HIV1 integrase. |
| 别名 | 埃替拉韦;GS-9137; JTK-303; EVG; D06677;6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
Elvitegravir(GS-9137,JTK-303),喹诺酮类HIV整合酶抑制剂
Elvitegravir (GS-9137, JTK-303) （订货以英文为准）
编号：E126129
CAS号：697761-98-1
分子式：C23H23CLFNO5
分子量：447.88
| 产品名称 | Elvitegravir (GS-9137, JTK-303) |
| 中文名称 | Elvitegravir(GS-9137,JTK-303),喹诺酮类HIV整合酶抑制剂 |
| CAS号 | 697761-98-1 |
| 分子式（M.F.） | C23H23CLFNO5 |
| 分子量（M.W.） | 447.88 |
| 储存条件 | 2-8°C储存 |
搜索质检报告(COA)
搜索MSDS
相关产品
党沛 
