| 敏感性 | 对湿度敏感 |
| 溶解性 | Soluble in DMSO or 5% acetic acid |
| 存贮条件 | 储存温度-20°C |
| 密度 | 1.3400 |
| 应用 | Chymostatin has been used in a study that determined that molecular calculations are useful for evaluating the interactions between ligands, including inhibitors and homologous enzymes, in docking models. Chymostatin has also been used in a study to investigate the norovirus protease as an attractive target for antiviral drug development. |
| 产品介绍 | Chymostatin is a bioactive peptide protease inhibitor that contains chymostatin A as a major form. The compound specifically inhibits chymotrypsin (CTR) (ID50 = 150 ηg/ml), papain (ID50 = 7.5 μg/ml), and cathepsin G along with most cysteine proteases such as cathepsin A, B, H, and L. The compound has been noted as a strong inhibitor of cathepsins A, B, and C. Chymostatin at an effective concentration of 10 to 100 μM weakly inhibits human leukocyte Elastase-1. In rat muscle homogenates chymostatin inhibited the protease cathepsin B and other soluble Ca2+ activated proteases. In the same study, chymostatin decreased protein break down by 20-40% without inhibiting protein production. |
| 生化机理 | 抑制溶酶体组织蛋白酶 B 和可溶性钙激活蛋白酶。许多幼嫩的植物组织都表达一种胰凝乳蛋白酶抑制剂敏感性丝氨酸蛋白酶。 糜蛋白酶抑制蛋白是许多蛋白酶的强抑制剂，包括糜蛋白酶、木瓜蛋白酶、糜蛋白酶样丝氨酸蛋白酶、糜蛋白酶和溶酶体半胱氨酸蛋白酶如组织蛋白酶 A、B、C、B、H 和 L。它对人白细胞弹性蛋白酶的抑制作用较弱。在终浓度为 100～200 μg/ml (10～100 μM) 时有效。胰凝乳蛋白酶抑制剂通常包含在与植物提取物一起使用的蛋白酶抑制剂混合物中。 |
| 别名 | N-（Nα-羰基-Cpd-X-Phe-al）-Phe（Cpd = 环氧环氧环己烷）（环氧环氧环己烷= [S，S]-α-（2-亚氨基六氢-4-嘧啶基）甘氨酸）;N-(Nα-Carbonyl-Cpd-X-Phe-al)-Phe (Cpd = capreomycidine) (capreomycidine = [S,S]-α-(2-Iminohexahydro-4-pyrimidyl)glycine) |
胰凝乳蛋白酶抑制剂
Chymostatin （订货以英文为准）
编号：C113165
CAS号：9076-44-2
分子式：C31H41N7O6
分子量：607.70
| 产品名称 | Chymostatin |
| 中文名称 | 胰凝乳蛋白酶抑制剂 |
| CAS号 | 9076-44-2 |
| 分子式（M.F.） | C31H41N7O6 |
| 分子量（M.W.） | 607.70 |
| 储存条件 | -20°C储存 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Danger |
| 危害声明 | H315,H319,H334,H335 |
| 警示性声明 | P261,P305+P351+P338,P342+P311 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| RTECS | YN5075000 |
| WGK德国 | 1 |
| 风险声明 (欧洲) | R36/37/38;R42 |
| 安全声明（欧洲） | S22;S24;S26;S36/37 |
| 危害码（欧洲） | Xn |
搜索质检报告(COA)
搜索MSDS
相关产品
¥ 103.90
T117926-25ml
¥ 1441.90
H128453-1g
¥ 2266.90
H128454-10UN
¥ 557.90
A118327-100mg
¥ 680.90
M139683-5KU
党沛 
