| 溶解性 | DMSO 88 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 应用 | A potent and selective inhibitor of Flk-1, PDGFR and c-kit |
| 产品介绍 | Pazopanib is a potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (Flk-1), platelet-derived growth factor receptor (PDGFR) and c-kit, which are key proteins responsible for tumor growth and angiogenesis. |
| 备注 | Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR-α/β, and c-Kit. |
| 生化机理 | Pazopanib is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. |
| 别名 | VEGFR抑制剂;帕唑帕尼;GW 786034;Votrient;GW-786034;GW786034;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide |
帕唑帕尼
Pazopanib （订货以英文为准）
编号：P125184
CAS号：444731-52-6
分子式：C21H23N7O2S
分子量：437.53
| 产品名称 | Pazopanib |
| 中文名称 | 帕唑帕尼 |
| CAS号 | 444731-52-6 |
| 分子式（M.F.） | C21H23N7O2S |
| 分子量（M.W.） | 437.53 |
| 储存条件 | -20°C储存 |
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