| 溶解性 | Soluble in water (>500 mg/ml), PBS (pH 7.2) (≥10 mg/ml), ethanol (≥20 mg/ml), DMSO (100 mM), and DMF (≥20 mg/ml). |
| 应用 | A specific antagonist of the AT1 receptor with significant downstream effects. |
| 备注 | Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
| 生化机理 | Losartan Potassium is a specific antagonist of the angiotensin II receptor subtype AT1. Antagonism of the AT1 receptor and interference of association between AT1 and angiotensin II produces vasodilation and reduction of hypertension. This antagonism has other downstream effects, including a correlated antagonism of the thromboxane A2 receptor, inhibition of platelet aggregation, and induction of peroxisome proliferator-actived receptor gamma (PPARγ) activity. |
| 别名 | 2-丁基-4-氯-1-{[2′-(1H-四唑-5-基)(1,1′-联苯)-4-基]甲基}-1H-咪唑-5-甲醇 单钾盐;2-丁基-4-氯-5-(羟甲基)-[[2'-(1H-四氮唑-5-基)联苯-4-基]甲基]咪唑钾;洛沙坦钾;氯沙坦钾;potassium[2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol;DuP-753 potassium; Cozaar potassium |
氯沙坦钾
Losartan Potassium (DuP 753) （订货以英文为准）
编号：L129227
CAS号：124750-99-8
分子式：C22H23CLKN6O
分子量：462.01
| 产品名称 | Losartan Potassium (DuP 753) |
| 中文名称 | 氯沙坦钾 |
| CAS号 | 124750-99-8 |
| 分子式（M.F.） | C22H23CLKN6O |
| 分子量（M.W.） | 462.01 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Danger |
| 危害声明 | H360 |
| 警示性声明 | P201-P308 + P313 |
| 个人防护设备 | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
| RTECS | KG5793000 |
| WGK德国 | 3 |
搜索质检报告(COA)
搜索MSDS
相关产品
¥ 120.00
sh024430-250mL
¥ 155.00
F903483-100g
¥ 2750.00
sh246789-100kg
¥ 128.00
sh7651-500mL
¥ 128.00
sh8754-500mL
¥ 128.00
sh42798-500mL
党沛 
