沸点 | 208℃ |
熔点 | 77-79°C |
敏感性 | 对光敏感 |
溶解性 | Soluble in water (600 g/L) at 20 °C, and alcohol. |
存贮条件 | 储存温度 -20℃ |
密度 | 2.2694 |
应用 | 有机合成,酶的抑制剂,测定疏基。蛋白质中半胱氨酸残基的改性剂 |
产品介绍 | Iodoacetic acid is a reagent for the modification and alkylation of cysteine residues in proteins. It has also been used in glycopeptide synthesis. |
备注 | For the chemical modification of thiol groups in proteins (specific for cysteine at pH 8.5) ; Alkylates methionine |
生化机理 | Iodoacetic acid (IAA) blocks the thiol group of cysteine. IAA inhibits glyceraldehyde-3-phosphate dehydrogenase (G3PDH) by interacting with sulfhydryl group of the active site cysteine. IAA inhibits the progression of solid Ehrlich carcinoma. IAA is one of the iodinated disinfection byproducts in drinking water. It is cytotoxic to mammalian cells. |
别名 | 碘代醋酸; |
碘乙酸
Iodoacetic acid (订货以英文为准)
编号:I104613
CAS号:64-69-7
分子式:C2H3IO2
分子量:185.95
产品名称 | Iodoacetic acid |
中文名称 | 碘乙酸 |
CAS号 | 64-69-7 |
MDL编码 | MFCD00002685 |
分子式(M.F.) | C2H3IO2 |
分子量(M.W.) | 185.95 |
Reaxys-RN | 1072826 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H315,H319,H335 |
警示性声明 | P261,P305+P351+P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | XU1645000 |
WGK德国 | 3 |
风险声明 (欧洲) | R36/37/38 |
安全声明(欧洲) | S26;S36 |
危害码(欧洲) | Xi |
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