| 生化机理 | It is an inhibitor of thymidine phosphorylase activity. It is also a potent and selective inhibitor of 4-nitrophenol glucuronidation. |
| 别名 | 5-硝基-4,6-嘧啶二醇;5-硝基-4,6-二羟基嘧啶;5-Nitro-4,6-pyrimidinediol; 5-nitropyrimidine-4,6-diol |
4,6-二羟基-5-硝基嘧啶
4,6-Dihydroxy-5-nitropyrimidine （订货以英文为准）
编号：D155133
CAS号：2164-83-2
分子式：C4H3N3O4
分子量：157.09
| 产品名称 | 4,6-Dihydroxy-5-nitropyrimidine |
| 中文名称 | 4,6-二羟基-5-硝基嘧啶 |
| CAS号 | 2164-83-2 |
| MDL编码 | D155133 |
| 分子式（M.F.） | C4H3N3O4 |
| 分子量（M.W.） | 157.09 |
| Reaxys-RN | 517132 |
技术规格
| Background: | Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. |
| Applications: | WB, IHC, IF |
| Name of antibody: | EIF2AK2 (Phospho-Thr446) |
| Immunogen: | Synthetic peptide of human EIF2AK2 (Phospho-Thr446) |
| Full name: | eukaryotic translation initiation factor 2-alpha kinase 2 (Phospho-Thr446) |
| Synonyms： | PKR; PRKR; EIF2AK1 |
| SwissProt: | P19525 |
| IHC positive control: | Human colon carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 62 kDa |
| WB Positive control: | K562 cells |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution | 100-200 |
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