熔点 | 256-257°C |
存贮条件 | 储存温度:2-8°C |
应用 | A triterpene with a pentacyclic ring structure.It can be used in the preparation of betulinic acid,which shows anti-HIV, antimalarial and anti-inflammatory activities. |
生化机理 | Betulin is a triterpene with a pentacyclic ring structure and hydroxyl groups in positions C3 and C28. Studies indicate that Betulin can effect intracellular signaling in ethanol-induced liver cells via inhibiting ROS, TNFα and TNFβ. In human cancer cells Betulin can induce mitochondrial cytochrome C release in human cancer cells, which results in apoptosis. Alternate studies on mice show that Betulin binds to melanocortin receptors and antagonizes the release of cAMP generation in mouse melanoma cells. Furthermore, Betulin has protective effects against cadmium induced apoptosis in human hepatoma cell lines. This occurs by inhibiting the activation of ROS, blocking Bid activation and suppressing the mitochondrial pathway. |
别名 | 白桦脂醇;桦木醇Lup-20(29)-ene-3β,28-diol |
桦木脑
Betulin (订货以英文为准)
编号:B129170
CAS号:473-98-3
分子式:C30H50O2
分子量:442.72
产品名称 | Betulin |
中文名称 | 桦木脑 |
CAS号 | 473-98-3 |
分子式(M.F.) | C30H50O2 |
分子量(M.W.) | 442.72 |
储存条件 | 2-8°C储存 |
Reaxys-RN | 1749573 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs09.jpg |
信号词 | Warning |
危害声明 | H319,H410 |
警示性声明 | P273,P305+P351+P338,P501 |
个人防护设备 | Eyeshields,Gloves,half-mask respirator (EU),half-mask respirator (US),multi-purpose combination respirator cartridge (US) |
RTECS | YQ2820000 |
WGK德国 | 2 |
闪点(摄氏) | 106°C |
风险声明 (欧洲) | R51/53 |
安全声明(欧洲) | S23;S24/25;S61 |
危害码(欧洲) | N |
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