熔点 | 65°C |
溶解性 | Soluble in ethanol (≥30 mg/mL), ether, chloroform, benzene, DMSO (≥30 mg/mL), DMF (≥30 mg/mL), and PBS (pH 7.2) (≥0.1 mg/mL). Insoluble in water. |
存贮条件 | 储存温度 2-8°C |
密度 | 1.0410 |
应用 | A TRPV1 receptor agonist |
产品介绍 | Capsaicin acts as an agonist at the VR1 (TRPV1) receptor, a ligand-gated non-selective cation channel. It exhibits neuroprotective effects in a model of transient global cerebral ischemia and induces release of substance P from afferent nociceptive specific neurons. Capsaicin also Inhibits NFκB activation by TNF and reversibly inhibits platelet aggregation. Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection. |
生化机理 | 原型辣椒素受体激动剂。神经毒素;激活感觉神经元生成许多包含P物质无髓C纤维,局部应用麻痹感觉神经末梢会给人一种矛盾的抗伤害效果;全身给药对辣椒素敏感的细胞具神经毒性,尤其是在新生动物。辣椒的活性成分。 |
别名 | 8-甲基-N-[(4-羟基-3-甲氧基苯基)-甲基]-(反)-6-壬烯基酰胺;8-甲基-N-香草基-L-壬烯胺;(E)-N-(4-羟基-3-甲氧基苄基)-8-甲基-6-壬烯酰胺;辣椒素;8-甲基-N-香草基-反-6-壬烯酰胺8-Methyl-N-vanillyl-6-nonenamide;N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide;(E)-Capsaicin |
天然辣椒碱
Capsaicin (订货以英文为准)
编号:C107693
CAS号:404-86-4
分子式:C17H27NO3
分子量:293.40
产品名称 | Capsaicin |
中文名称 | 天然辣椒碱 |
CAS号 | 404-86-4 |
分子式(M.F.) | C17H27NO3 |
分子量(M.W.) | 293.40 |
储存条件 | 2-8°C储存 |
Reaxys-RN | 165289 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H302,H315,H319,H335 |
警示性声明 | P261,P305+P351+P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
WGK德国 | 3 |
风险声明 (欧洲) | R22;R36/37/38 |
安全声明(欧洲) | S26;S36/37 |
危害码(欧洲) | Xn |
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