BMY 7378 二盐酸盐

BMY 7378 dihydrochloride (订货以英文为准)

编号:B129688
CAS号:21102-95-4
分子式:C22H33CL2N3O3
分子量:458.42
货号 品牌 包装 目录价 您的价格 库存 数量 购买
B129688-10mg 阿拉丁 10mg ¥292.90
B129688-100mg 阿拉丁 100mg ¥1750.90
B129688-50mg 阿拉丁 50mg ¥1010.90
产品名称 BMY 7378 dihydrochloride
中文名称 BMY 7378 二盐酸盐
CAS号 21102-95-4
分子式(M.F.) C22H33CL2N3O3
分子量(M.W.) 458.42
储存条件 2-8°C储存
熔点196.5-198.5 °C
溶解性Soluble in water (5 mg/ml), DMSO (92 mg/ml), and ethanol (20 mg/ml).
存贮条件储存温度2-8°C
应用A SR-1A agonist and a selective α1D-AR antagonist.
产品介绍BMY 7378是一种多靶点抑制剂,作用于α2C-adrenoceptor和α1D-adrenoceptor,pKi分别为6.54和8.2,且为混合型5-HT1A受体激动剂和拮抗剂,pKi为8.3。
备注BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3
生化机理BMY 7378 dihydrochloride is a putative SR-1A (5-HT1A) partial agonist, and high affinity α1D-AR adrenoceptor antagonist.
别名8-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-8-氮杂螺[4.5]癸烷-7,9-二酮盐酸盐;BMY 7378; 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride;N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride;BMY 7378
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