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钙调素 来源于牛睾丸

Calmodulin from bovine testes （订货以英文为准）

编号：C140110
CAS号：77107-46-1
货号 品牌 包装 目录价 您的价格 库存 数量 购买
C140110-2.5mg 阿拉丁 2.5mg ¥6179.90
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C140110-1mg 阿拉丁 1mg ¥3089.90
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产品名称 Calmodulin from bovine testes
中文名称 钙调素 来源于牛睾丸
CAS号 77107-46-1
储存条件 -20°C储存
存贮条件储存温度-20°C
应用Protein calcium binding studies on the regulation of a multitude of different protein targets; Activation of cyclic nucleotide-dependent phosphodiesterase; Co-factor/activator for kinase studies; Studies of edema factor toxin and anthrax bacteria
产品介绍Calmodulin is a bioactive protein isolated from bovine testes with a molecular weight of 16,7 kDa. The material is derived from cattle born and raised in Sweden, a country where BSE is non-existing. Calmodulin is a calcium-binding protein expressed in many eukaryotic cells. By binding to and regulating various protein targets, it affects cellular processes such as metabolism, nerve growth, apoptosis, inflammation, muscle contraction and memory. Many proteins use Calmodulin as a calcium sensor and signal transducer, as the proteins themselves are not able to bind calcium. The molecule can bind a maximum of four calcium ions and by undergoing post-translational modifications such as acetylation, phosphorylation, proteolytic cleavage and methylation, its functions can potentially be altered. Calmodulin is supplied as a lyophilized white powder or flocculate from 50 mM NH4HCO3 with 10 μM CaCl2. No preservatives are added. The protein content is analyzed by amino acid assay and is never less than 80 % of weighed substance. The material has been subjected to an acid treatment for minimum 30 min. The protein is derived from a single batch and is homogenous.
生化机理环核苷酸依赖性磷酸二酯酶活化所需的 Ca2+ 结合蛋白。它也是一氧化氮合成酶、钙调磷酸酶以及多种激酶的辅因子/活化剂，这些激酶包括 ATP 酶、肌球蛋白轻链激酶和 CAM 激酶 I、II、III。它通过环二磷酸腺苷核糖介导利阿诺定受体活化并且与细胞内 Ca2+ 的内稳态有关。
别名CaM 磷酸二酯酶 3′:5′-环核苷酸活化剂;CaM, Phosphodiesterase 3′:5′-cyclic nucleotide activator
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