| 熔点 | 225-230°C |
| 溶解性 | Soluble in ethanol (25 mM), DMSO (10 mM), chloroform (very slightly), and methanol: acetone (1: 1) (50 mg/ml). Insoluble in water. |
| 应用 | An inhibitor of the Stat3 signaling pathway and also a FRAP inhibitor. |
| 产品介绍 | Niclosamide is an inhibitor of the Stat3 signaling pathway. Niclosamide inhibits the activation, nuclear translocation and transactivation of Stat3. Niclosamide displays selectivity for Stat3 over Stat1, Stat5, JAK1, JAK2 and Src kinases. Niclosamide inhibits the transcription of Stat3 target genes and induces cell growth inhibition, apoptosis and cell cycle arrest of cancer cells with constitutively active Stat3. Niclosamide is also a FRAP inhibitor via reversible inhibition of mTORC1 signaling and stimulates autophagy in vitro. Niclosamide displays antineoplastic effects in acute myelogenous leukemia (AML) stem cells. |
| 别名 | 2',5-二氯-4'-硝基水杨酸酰替苯胺;4'-硝基-2',5-二氯水杨酰苯胺;百螺杀;见螺杀;血防-67;灭绦录2′,5-Dichloro-4′-nitrosalicylanilide;5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide |
氯硝柳胺
Niclosamide （订货以英文为准）
编号：N130841
CAS号：50-65-7
分子式：C13H8CL2N2O4
分子量：327.12
| 产品名称 | Niclosamide |
| 中文名称 | 氯硝柳胺 |
| CAS号 | 50-65-7 |
| MDL编码 | MFCD00057597 |
| 分子式（M.F.） | C13H8CL2N2O4 |
| 分子量（M.W.） | 327.12 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Danger |
| 危害声明 | H315,H319,H360 |
| 警示性声明 | P201,P305+P351+P338,P308+P313 |
| 个人防护设备 | Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P2 (EN 143) respirator cartridges,type P3 (EN 143) respirator cartridges |
| WGK德国 | 3 |
| 风险声明 (欧洲) | R35;R61; |
| 安全声明（欧洲） | 53,26,36/37/39,45 |
| 危害码（欧洲） | T |
搜索质检报告(COA)
搜索MSDS
相关产品
¥ 3.00
XGS-J2-1双
¥ 800.00
TA384138-20ul
¥ 616.00
PAB516Mu01-20ul
¥ 40.00
sh031201-1卷
党沛 
