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4-溴-α-氯苄基磷酸二苯酯

Diphenyl 4-Bromo-α-chlorobenzylphosphonate （订货以英文为准）

编号：D155193
CAS号：189099-56-7
分子式：C19H15BRCLO3P
分子量：437.65
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D155193-25g 阿拉丁 25g ¥2929.90
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D155193-5g 阿拉丁 5g ¥739.90
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D155193-1g 阿拉丁 1g ¥264.90
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产品名称 Diphenyl 4-Bromo-α-chlorobenzylphosphonate
中文名称 4-溴-α-氯苄基磷酸二苯酯
CAS号 189099-56-7
MDL编码 D155193
分子式（M.F.） C19H15BRCLO3P
分子量（M.W.） 437.65
储存条件 充氩
熔点107°C(lit.)
别名;['4-Bromo-α-chlorobenzylphosphonic Acid Diphenyl Ester']
Reaxys-RN1543618
信号词Danger
危害声明H301
警示性声明P301 + P310
WGK德国3

技术规格

Background: Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.
Applications: WB, IHC
Name of antibody: CHUK
Immunogen: Synthetic peptide of human CHUK (Ab-23)
Full name: conserved helix-loop-helix ubiquitous kinase
Synonyms： IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
SwissProt: O15111
IHC positive control: Human colon carcinoma
IHC Recommend dilution: 50-100
WB Predicted band size: 85 kDa
WB Positive control: Hela, 293 and 3T3 cells
WB Recommended dilution: 500-1000
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