| 别名 | 4,6-二氨基嘧啶-2-硫醇; |
4,6-二氨基-2-巯基嘧啶
4,6-Diamino-2-mercaptopyrimidine （订货以英文为准）
编号：D155134
CAS号：1004-39-3
分子式：C4H6N4S
分子量：142.18
| 产品名称 | 4,6-Diamino-2-mercaptopyrimidine |
| 中文名称 | 4,6-二氨基-2-巯基嘧啶 |
| CAS号 | 1004-39-3 |
| 分子式（M.F.） | C4H6N4S |
| 分子量（M.W.） | 142.18 |
| Reaxys-RN | 471676 |
| RTECS | XU5950000 |
技术规格
| Background: | Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| Applications: | WB |
| Name of antibody: | ITGB3 (Phospho-Tyr785) |
| Immunogen: | Synthetic peptide of human ITGB3 (Phospho-Tyr785) |
| Full name: | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) (Phospho-Tyr785) |
| Synonyms： | GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16 |
| SwissProt: | P05106 |
| WB Predicted band size: | 87 kDa |
| WB Positive control: | HUVEC cells |
| WB Recommended dilution: | 500-1000 |
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