4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶(AT7867)

AT7867 (订货以英文为准)

编号:A126209
CAS号:857531-00-1
分子式:C20H20CLN3
分子量:337.86
货号 品牌 包装 目录价 您的价格 库存 数量 购买
A126209-5mg 阿拉丁 5mg ¥143.90
A126209-10mg 阿拉丁 10mg ¥272.90
A126209-50mg 阿拉丁 50mg ¥669.90
产品名称 AT7867
中文名称 4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶(AT7867)
CAS号 857531-00-1
分子式(M.F.) C20H20CLN3
分子量(M.W.) 337.86
储存条件 -20°C储存
沸点530.2 °C/760 mmHg
溶解性DMSO ≥66mg/mL Water <1.2mg/mL Ethanol ≥4.6mg/mL
存贮条件储存温度-20°C
密度1.2000
应用A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3
产品介绍AT7867是ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂,IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM,对AGC激酶家族以外的蛋白几乎无活性。
备注AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.
生化机理AT7867 is a potent and oral AKT and p70 S6 kinase inhibitor with an IC50 of 17 nM.
别名4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶;pyrazole-based inhibitor 9;4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine
搜索质检报告(COA)
搜索MSDS
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