| 沸点 | 153°C/0.1mmHg |
| 密度 | 1.2400 |
| 别名 | 二乙基(4-硝基苯甲基)磷酸盐;Diethyl (4-nitrobenzyl)phosphonate;(4-Nitrobenzyl)phosphonic Acid Diethyl Ester |
4-(硝基苄基)膦酸二乙酯
Diethyl (4-Nitrobenzyl)phosphonate （订货以英文为准）
编号：D155179
CAS号：2609-49-6
分子式：C11H16NO5P
分子量：273.22
| 产品名称 | Diethyl (4-Nitrobenzyl)phosphonate |
| 中文名称 | 4-(硝基苄基)膦酸二乙酯 |
| CAS号 | 2609-49-6 |
| 分子式（M.F.） | C11H16NO5P |
| 分子量（M.W.） | 273.22 |
| 储存条件 | 2-8°C储存 |
| Reaxys-RN | 3581786 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
| 信号词 | Warning |
| 危害声明 | H302,H312,H315,H319,H332,H335 |
| 警示性声明 | P261,P280,P305+P351+P338 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
| WGK德国 | 3 |
| 风险声明 (欧洲) | R20/21/22;R36/37/38 |
| 安全声明（欧洲） | S26;S37/39 |
| 危害码（欧洲） | Xn |
技术规格
| Background: | MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Applications: | WB |
| Name of antibody: | MAPK14 (Phospho-Thr180/Tyr182) |
| Immunogen: | Synthetic peptide of human MAPK14 (Phospho-Thr180/Tyr182) |
| Full name: | mitogen-activated protein kinase 14 (Phospho-Thr180/Tyr182) |
| Synonyms： | RP1-179N16.5; CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; P38alpha |
| SwissProt: | Q16539 |
| WB Predicted band size: | 43 kDa |
| WB Positive control: | Hela cells treated with TNFα+CA |
| WB Recommended dilution: | 500-1000 |
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