| 别名 | ; |
4'-癸氧基联苯-4-羧酸
4'-Decyloxybiphenyl-4-carboxylic Acid （订货以英文为准）
编号：D155157
CAS号：69367-32-4
分子式：C23H30O3
分子量：354.48
| 产品名称 | 4'-Decyloxybiphenyl-4-carboxylic Acid |
| 中文名称 | 4'-癸氧基联苯-4-羧酸 |
| CAS号 | 69367-32-4 |
| MDL编码 | D155157 |
| 分子式（M.F.） | C23H30O3 |
| 分子量（M.W.） | 354.48 |
| Reaxys-RN | 11532701 |
技术规格
| Background: | General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase. |
| Applications: | WB, IHC, IF |
| Name of antibody: | AKT1 (phospho-Thr450) |
| Immunogen: | Synthetic peptide of human AKT1 (phospho-Thr450) |
| Full name: | v-akt murine thymoma viral oncogene homolog 1 (phospho-Thr450) |
| Synonyms： | AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA |
| SwissProt: | P31749 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 60 kDa |
| WB Positive control: | 293 cells treated with EGF |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution | 100-200 |
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