应用 | A muscarinic antagonist. |
别名 | 1,1-二苯基-4-(1-哌啶基)-1-丁醇盐酸盐;盐酸地芬尼多;西法多霉素;Diphenidol Hydrochloride;1-(4-Hydroxy-4,4-diphenylbutyl)piperidine Hydrochloride |
1,1-联苯-4-哌啶基-1-丁醇盐酸盐
1,1-Diphenyl-4-piperidino-1-butanol Hydrochloride (订货以英文为准)
编号:D124789
CAS号:3254-89-5
分子式:C21H27NO.HCL
分子量:345.91
产品名称 | 1,1-Diphenyl-4-piperidino-1-butanol Hydrochloride |
中文名称 | 1,1-联苯-4-哌啶基-1-丁醇盐酸盐 |
CAS号 | 3254-89-5 |
MDL编码 | MFCD00151479 |
分子式(M.F.) | C21H27NO.HCL |
分子量(M.W.) | 345.91 |
风险声明 (欧洲) | R36/37/38 |
安全声明(欧洲) | S26,S37 |
技术规格
Background: | Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]). |
Applications: | ELISA, IHC |
Name of antibody: | DENND1B |
Immunogen: | Fusion protein of human DENND1B |
Full name: | DENN domain containing 1B |
Synonyms: | FAM31B; C1ORF18; C1orf218 |
SwissProt: | Q6P3S1 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human thyroid cancer;Human esophagus cancer |
IHC Recommend dilution: | 20-100 |
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