敏感性 | 对光线敏感 |
溶解性 | Soluble in DMSO (25 mg/ml), and methanol (5 mg/ml). |
存贮条件 | 储存温度 -20°C |
应用 | Selectively inhibits arachidonoyl-CoA synthetase in intact cells.Inhibits the nonspecific acyl-CoA synthetase in cell sonicatesIC50=3.6-8.7 μM1–3. Inhibits neutrophil functions |
产品介绍 | Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator. |
生化机理 | Triacsin C is a potent inhibitor of long-chain fatty acyl CoA synthetase. It blocks β-cell apoptosis, induced by fatty acids (lipoapoptosis) in a rat model of obesity. In addition, it blocks the de novo synthesis of triglycerides, diglycerides, and cholesterol esters, thus interfering with lipid metabolism. |
别名 | ;2E, 4E, 7E-Undecatriene-1-triazene; 2,4,7-Undecatrienal nitrosohydrazone WS1228A |
Triacsin C,来自链霉菌属
Triacsin C from Streptomyces sp. (订货以英文为准)
编号:T139793
CAS号:76896-80-5
分子式:C11H17N3O
分子量:207.27
产品名称 | Triacsin C from Streptomyces sp. |
中文名称 | Triacsin C,来自链霉菌属 |
CAS号 | 76896-80-5 |
分子式(M.F.) | C11H17N3O |
分子量(M.W.) | 207.27 |
储存条件 | 避光;-20°C储存;充氩 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H317 |
警示性声明 | P280 |
个人防护设备 | dust mask type N95 (US),Eyeshields,Faceshields,Gloves |
RTECS | QI7700000 |
WGK德国 | 2 |
风险声明 (欧洲) | R43; |
安全声明(欧洲) | S36/37; |
危害码(欧洲) | Xi |
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